5 WARNINGS AND PRECAUTIONS
Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur.
8.1 Pregnancy
However, elderly patients are more sensitive to the effects of this medicine than younger adults. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.
Comparison with actions of other PDE5 inhibitors
When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.
Mechanism of Action
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. Your doctor may adjust your dose as needed. For treatment of erectile dysfunction (daily use):Adults—2.5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity. Adults—2.5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity.
| Aspect | Description | Common Uses | Key Benefits |
|---|---|---|---|
| Active Ingredient | Tadalafil | Erectile Dysfunction | Longer-lasting effects |
| Dosage | 10 mg per tablet | BPH (Benign Prostatic Hyperplasia) | Once daily or as needed |
| Onset of Action | Typically within 30-60 minutes | Fast relief | |
| Duration of Effect | Up to 36 hours | Extended window of efficacy | |
| Approval Year | 2003 | FDA approved |
For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Super Active | 20mg | 90 + 10 Pills | 314.14€ 299.18€ | |
| Cialis Original | 20mg | 48 + 4 Pills | 224.69€ 213.99€ | |
| Cialis Generic | 40mg | 30 + 4 Pills | 74.97€ 71.40€ | |
| Cialis Original | 20mg | 120 + 8 Pills | 497.29€ 473.61€ | |
| Cialis Generic | 5mg | 180 + 10 Pills | 159.65€ 152.05€ | |
| Cialis Generic | 5mg | 60 + 4 Pills | 86.02€ 81.92€ | |
| Cialis Soft Tabs | 20mg | 60 + 4 Pills | 159.37€ 151.78€ | |
| Cialis Professional | 40mg | 270 + 6 Pills | 898.37€ 855.59€ | |
| Cialis Generic | 20mg | 90 + 6 Pills | 154.71€ 147.34€ | |
| Cialis Generic | 2.5mg | 10 Pills | 28.51€ 27.15€ | |
| Cialis Generic | 5mg | 20 Pills | 41.99€ 39.99€ | |
| Cialis Black | 80mg | 20 Pills | 71.83€ 68.41€ | |
| Cialis Black | 80mg | 270 + 10 Pills | 502.88€ 478.93€ | |
| Cialis Professional | 20mg | 60 + 2 Pills | 183.83€ 175.08€ | |
| Cialis Super Active | 20mg | 20 + 4 Pills | 92.35€ 87.95€ | |
| Cialis Professional | 40mg | 120 + 4 Pills | 436.68€ 415.89€ |
Adults—5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity.
5.4 Eye
Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions. You may take this medicine with or without food. Do not split, break, chew, or crush it. Chewable tablets: Chew the tablet completely before swallowing.
Canadian Brand Name
When using this medicine for erectile dysfunction, the ability to have sexual activity may be improved for up to 36 hours after taking the tablet. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body.
Warnings for other groups
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. For treatment of pulmonary arterial hypertension:Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day. Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day. Children—Use and dose must be determined by your doctor.
- The environmental impact of pharmaceutical excretion is a concern.
- Trace amounts of Tadalafil can be found in wastewater.
- Its effects on aquatic life are not fully understood.
- Advanced water treatment plants can remove a significant portion.
- Proper disposal of unused medication helps minimize environmental contamination.
- The synthesis of Tadalafil is a multi-step chemical process.
- The starting material is often D-tryptophan methyl ester.
- The manufacturing process is subject to strict Good Manufacturing Practice (GMP).
- Quality control ensures each tablet contains the precise 10mg dose.
- Stability testing determines the shelf life of the product.
- Packaging is designed to protect the tablets from moisture and light.
- Batch numbers and expiration dates are printed on every package.
For treatment of benign prostatic hyperplasia (daily use): For oral dosage form (chewable tablet):For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day. Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction (as needed):Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended. For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day.
7.2 Potential for Other Drugs to Affect CIALIS
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (tablets):For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) as a single dose, no more than once a day, taken at the same time each day.Children—Use is not recommended.For treatment of erectile dysfunction (as needed):Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction (daily use):Adults—2.5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity. Your doctor may adjust your dose as needed.Children—Use is not recommended.For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended.For treatment of pulmonary arterial hypertension:Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day. Take both tablets at the same time each day. Adults—5 milligrams (mg) once a day, taken at about the same time each day. For treatment of erectile dysfunction and benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) once a day, taken at about the same time each day, without regard for the timing of sexual activity.Children—Use is not recommended.
2.3 CIALIS for Once Daily Use for Benign Prostatic Hyperplasia
Your doctor may adjust your dose as needed.Children—Use and dose must be determined by your doctor. For treatment of benign prostatic hyperplasia (daily use):Adults—5 milligrams (mg) as a single dose, no more than once a day, taken at the same time each day.Children—Use is not recommended. Adults—5 milligrams (mg) as a single dose, no more than once a day, taken at the same time each day. For treatment of erectile dysfunction (as needed):Adults—10 milligrams (mg) as a single dose, no more than once a day, taken 30 minutes before you think sexual activity may occur. Your doctor may adjust your dose as needed.Children—Use canadian pharmacy no prescription cialis is not recommended. Adults—5 milligrams (mg) once a day, taken at about the same time each day, without regard for the timing of sexual activity. For treatment of benign prostatic hyperplasia (daily use): If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Brand names
If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Abnormal penis, including curved penis and birth defects of the penis (eg, angulation, cavernosal fibrosis, or Peyronie’s disease) or Sickle-cell anemia (blood disorder)—Use with caution. May increase risk of unwanted side effects (eg, prolonged erection of the penis).
Provider: HealthWell Foundation Copay Program
Crowded optic disc or low cup to disc ratio in the eye (an eye disorder) or Hyperlipidemia (high lipids or fats in the blood) or Non-arteritic anterior ischemic optic neuropathy or NAION (serious eye condition), history of or May increase risk for non–arteritic anterior ischemic optic neuropathy (NAION). Blood vessel problems (eg, aortic stenosis, idiopathic subaortic stenosis) or Heart attack (within the last 3 months) or Heart failure (within the last 6 months) or Retinitis pigmentosa (an inherited eye disorder) or Stroke (within the last 6 months)—Should not be used in patients with these conditions. Stomach ulcers—Use must be determined by your doctor. Pulmonary veno-occlusive disease or PVOD (a type of lung roman cialis price disease)—Use with caution. Liver disease, mild or moderate—Use with caution.
Side effects and risks
The effects may be increased because of slower removal of the medicine from the body. Use tadalafil exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Also, do not stop taking this medicine without checking first with your doctor. This medicine comes with a patient information leaflet. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. It is important that you tell all of your doctors that you take tadalafil.
- The font used for the "C" and "10" imprint is specific to the manufacturer.
- Generic versions must have a different imprint to avoid trademark infringement.
- This helps pharmacists and patients identify the product and its strength.
- Pill identification tools are available online using these imprints.
- The tablet's dimensions are approximately 9.0 mm x 7.5 mm.
- The film coating ensures easy swallowing and masks any bitter taste.
- The excipients (inactive ingredients) are necessary for tablet formation.
- These include fillers, binders, disintegrants, and lubricants.
- Lactose is a common filler; those with lactose intolerance should be aware.
- The manufacturing process involves blending, granulation, compression, and coating.
- Each step is rigorously controlled to ensure product quality and safety.
- Final products are tested for dissolution rate to ensure proper absorption.
If you need emergency medical care for a heart problem, it is important that your doctor knows when you last took tadalafil.
| Parameter | Value | Notes |
|---|---|---|
| Absorption rate | Peak plasma concentration in about 2 hours | |
| Bioavailability | Approximately 36% | |
| Metabolism | Primarily via CYP3A4 enzyme | |
| Half-life | About 17.5 hours | Longer than many ED medications |
| Excretion | Mainly via feces (~61%) and urine (~36%) |
If you will be taking this medicine for pulmonary arterial hypertension, it is very important that your doctor check your progress at regular visits.