Do Under-The-Tongue Dissolvable ED Tablets Work Better Than Pills?

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The onset time determines how soon you can engage in intercourse.

When to See a Doctor

"There are some men in whom none of these drugs work," Dr. Liou says. How soon the drugs start working ranges from 15 to 60 minutes. Neither Viagra nor Levitra will work if you take them after a meal, which blocks their absorption. However, neither Cialis nor Stendra interact with food this way. Stendra and daily-use Cialis are closest to being an "on demand" erectile drug; using the others requires more planning.

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Dr.

Haven’t Been Feeling Like Yourself Lately?

Smoking cigarettes is linked to heart and blood vessel disease, which can lead to ED. Eating well helps to maintain erectile function. Consider working with a registered dietitian, if possible, to create an eating plan for your individual needs. You can find a registered dietitian online through the Academy of Nutrition and Dietetics or through your health care professional. A dietitian can create a custom meal plan for you.

Urethral suppository (Muse)

A healthy weight can improve testosterone levels and self-esteem, which may help prevent ED. Maintaining a healthy weight can also prevent diabetes and high blood pressure, which can cause ED. Physical activity increases blood flow through your body, including the penis, and can help keep you at a healthy weight. The Physical Activity Guidelines for Americans, 2nd edition, recommends at least 150 minutes, or 2 hours and 30 minutes, of moderate-intensity physical activity, such as brisk walking, each week.2 Taking care of your mental and emotional health can help prevent ED. If you feel stressed, try relaxation techniques and other activities that might soothe you.

Recreational use

A simple way to relax is deep breathing, which you can do anywhere. You can help prevent ED by avoiding recreational and illicit drugs and limiting how much alcohol you drink. Some drugs can prevent arousal or other sensations that are important for getting and keeping an erection. Sometimes, illicit drugs and too much alcohol may mask other mental health, emotional, or physical factors that cause ED. This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. Liou says that some men come to him after getting a prescription from their primary care doctors, claiming that the drug doesn't work.

Sometimes it's because they used it incorrectly. "The biggest misconception is that these drugs are an on/off switch for erections," Dr. Liou says. But the drugs don't work well without sexual stimulation. "During that time, you need to be with your partner and have foreplay," Dr. Liou says. "Don't take it, do the taxes or the dishes, and then meet at the bedroom thinking you'll be ready to go. The ED drugs break down at different rates in the body.

Make sure you take the right drug for you.

You'll need to work with your doctor to get the pill you need at a price you can afford. In addition to Viagra, other ED drugs available in the United States include avanafil (Stendra), tadalafil (Cialis) and vardenafil (Levitra). These all improve blood supply to the penis. In combination with sexual stimulation, the drugs can produce an erection sufficient to initiate and complete intercourse. There is also a fast-dissolving form of Levitra, called Staxyn, that you put under your tongue.

Best for fast action: Stendra

One ED drug, Cialis, is FDA-approved for use daily in a dose of 2.5 or 5 milligrams. This helps to produce erections on demand and may also help relieve urinary problems, like difficulty starting urination, that result from an enlarged prostate. The cost to you for ED drug therapy varies considerably, depending on the pharmacy price, prescription co-pays, and your level of health plan coverage. Even if private insurance covers it, you may be limited to four doses per month. Here are a few things you can do to contain costs: Various web-based tools can help you compare prices easily.

Why Are They Taken?

Ask your doctor about pill splitting, where you get the pills at a higher dose than you need and divide them. These allow you to obtain a limited supply of medications not covered by your insurance. ED drugs produce an erection sufficient for intercourse in about 70% of men. But the results vary quite a bit from one individual to another. A man with nerves or arteries damaged by prostate surgery, diabetes, or cardiovascular disease will not respond as strongly to ED drugs. The durations of action range from four hours to more than a day (for Cialis in the higher doses). Each dose should be sufficient to provide a full cycle of intercourse, from erection to climax. To have sex more than once a day, Cialis is your best bet.

Drug Name Active Ingredient Typical Dose Onset Time Duration of Action Common Uses Side Effects
Viagra Sildenafil 50 mg 30-60 min 4-6 hours Erectile dysfunction Headache, flushing
Cialis Tadalafil 20 mg 30 min Up to 36 hours ED, BPH Muscle pain, nausea
Levitra Vardenafil 10 mg 25-60 min 4-5 hours ED Nasal congestion
Stendra (Avanafil) Avanafil 100 mg 15 min Up to 6 hours Rapid onset ED Dizziness

The most common side effects of ED drugs, in order of most to least common are headache, flushing, upset stomach, nasal congestion, vision problems, diarrhea, dizziness, and rash.

Drug Mechanism of Action Receptor Target Effect Duration Additional Effects
Sildenafil PDE5 inhibitor, increases blood flow to the penis PDE5 4-6 hours Vasodilation, slight hypotension
Tadalafil PDE5 inhibitor, longer half-life PDE5 Up to 36 hours Smooth muscle relaxation
Vardenafil PDE5 inhibitor, similar to sildenafil PDE5 4-5 hours Minimal effects on blood pressure
Avanafil PDE5 inhibitor, fast-acting PDE5 6 hours Fewer visual side effects

A man who has an erection that lasts four hours or more needs to get to a hospital or risk permanent damage. None of the ED drugs is safe to take with cardiac drugs called nitrates because it could cause a dangerous drop in blood pressure. Drugs that many men take for urinary symptoms, called alpha blockers, can also lower blood pressure, so take them at least four hours apart from ED drugs. Your doctor may start you on a smaller dose of the ED drug if you already take an alpha blocker or may recommend the alpha blocker tamsulosin (Flomax), which affects blood pressure less. ED is often an early warning sign of underlying cardiovascular disease, such as clogged arteries (atherosclerosis). "It can predate a diagnosis of cardiovascular disease by at least a few years," Dr. Liou says. We don't have strong proof yet that starting to live a healthier lifestyle can reverse erectile problems, but it can't hurt. Read 5 natural ways to overcome erectile dysfunction. As a service to our readers, Harvard Health Publishing provides access to our library of archived content.

How to Take Sildenafil Correctly for Erectile Dysfunction

Your health care professional will teach you how to give yourself an injection or insert a suppository. Some people say certain alternative medicines help their ED symptoms. For safety reasons, talk with your health care professional before using dietary supplements, such as vitamin or mineral supplements, or any complementary or alternative medicines or medical practices. Vacuum erectile devices (VEDs) pull blood into the penis for an erection. a plastic tube to put around your penis an elastic ring that helps you to keep an erection You may need to practice with or adjust your VED.

How common is erectile dysfunction?

Sometimes, VEDs can make your penis feel cold or numb. Your penis could look purple or bruised. Bruises are usually painless and will disappear in a few days. VEDs may weaken ejaculation but this doesn’t affect the pleasure of climax or orgasm. Most people with ED do not need surgery.

Best injectable alternative: TriMix injection

If you have tried all other options and your ED does not improve, you and your health care professional may consider surgery to implant a device—called a prosthesis—to make the penis erect, either using a pump in the scrotum or a rod buy cenforce pills that you can control on your own repair arteries to increase blood flow to the penis, a procedure that works best for younger men Your health care professional will describe the benefits and possible side effects of surgery. ED medicines that you take by mouth, through an injection, or as a suppository can have side effects, including erections that last longer than 4 hours, known as priapism vision or hearing loss after taking oral ED medicines Call your health care professional right away if you develop these problems. Lifestyle factors can often lead to ED or make its symptoms worse. Sometimes, changing a daily habit could help prevent or improve your ED. If you smoke cigarettes, one of the best things you can do for your ED and your overall health is to quit smoking. Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Even if your high blood pressure (or hypertension) has caused erectile dysfunction (ED), you have every reason to be optimistic about the future and a healthy sex life.

8. MED3000 (Eroxon)

NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by NIDDK is carefully reviewed by NIDDK scientists and other experts. What are the differences between erectile dysfunction drugs? About half of men ages 40 to 70 have erectile dysfunction (ED) to some degree, although only one in 10 report a complete inability to have erections. Taking an ED drug produces an erection sufficient to start intercourse in about 70% of otherwise healthy men.

When should you take Tadalafil?

Does it make any difference which of the four drugs for erectile dysfunction you take? "Yes, there can be differences," says Dr. Louis Liou, chief of urology at Harvard-affiliated Cambridge Health Alliance in Boston. "For new patients, I have them try different ones to see what works best." Sildenafil (Viagra) is often the first drug your doctor offers. It's been on the market longest and its side effects and the medications and foods it interacts with are well known.

How does a man sustain an erection?

But the main challenge to finding the best ED drug for you may turn out to be health insurance rules—not biochemistry. It's a common practice among insurers to limit the number of pills you can obtain per month. After you hit your limit, the out-of-pocket cost for a single pill can be very high. "The main obstacle flibanserin in my practice is the cost," Dr. Liou says. ED is a common problem associated with high blood pressure, but there are many proven treatments you can try. A doctor's first choice for treating erection problems is usually one of the pills called PDE5 inhibitors. Now there's also Cialis, Levitra, and Staxyn. All of these drugs work in similar ways. They make it physically possible to get an erection when you are aroused. No one of them has been proven to work better than the others. But the time they take to start working and the duration of their effects vary.